what is nodular contour of the liverwhat is nodular contour of the liver

In the liver parenchyma, multiple nodular, hypodense lesions with III. Excess body fat can damage your liver. A doctor may recommend this noninvasive procedure if blood tests or symptoms suggest that you have a liver condition. General Practice 40 years experience. Micronodular cirrhosis refers to a form of cirrhosis that has uniform nodules. There is a vague hyperattenuating lesion within the right hepatic lobe (white arrow) with punctate focus of hypodensity, suggestive of fat (black arrowhead). Lesions such as tumors, abscesses, or cysts of the liver or spleen may be seen on a liver scan. Management of hepatocellular carcinoma is discussed elsewhere (see hepatocellular carcinoma). The scar tissue blocks the flow of blood through the liver and slows the livers ability to process nutrients, hormones, drugs and natural toxins (poisons). A tumor is an abnormal growth of cells or tissues. We want you to take advantage of everything Cancer Therapy Advisor has to offer. Additional complications of portal hypertension include: Hypersplenism: Hypersplenism is an overactive spleen. Jaundice causes yellowing of the skin and whites of the eyes and darkening of urine. The assessment and management of pain in cirrhosis. I. Problem/Condition. Cirrhosis is a late-stage liver disease in which healthy liver tissue is replaced with scar tissue and the liver is permanently damaged. It affects about 1 in 200 adults age 45 to 54, the age group most commonly affected by cirrhosis. They can also be used to look at blood vessels in and around the liver to see any blockages, and can help show if liver cancer has spread to other parts of the body. Your liver can regenerate and heal itself. b. On rare occasions, they can become large enough to press on nearby organs. Accessed 10/11/2020. The short answer is no. 3.23 cm lobulated hypoechoic lesion is seen in the right lobe. The contours of the liver appear nodular and undulating (Figure 11.7). The most significant complication of liver fibrosis can be liver cirrhosis, or severe scarring that makes the liver so damaged a person will become sick. 5-year relative survival rates for liver cancer. There are different options available to treat cancerous liver lesions: Signs that your liver is not functioning properly include fatigue, abdominal pain, jaundice and other symptoms and signs. A liver ultrasound will allow your doctor to see the size, shape, and texture of your liver. (https://www.gastroenterologyandhepatology.net/archives/august-2019/the-gastroenterologists-guide-to-preventive-management-of-compensated-cirrhosis/), (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904420/), (https://www.merckmanuals.com/professional/pulmonary-disorders/pulmonary-hypertension/hepatopulmonary-syndrome). Higher level of iron (may indicate hemochromatosis). It also reduces the production of proteins and other substances made by the liver. In some cases, surgery may be used to remove cancerous tissue from the liver. To view unlimited content, log in or register for free. Liver biopsy from a young woman with juvenile hemochromatosis due to mutations in HFE2. However, the tumor must be small and confined. 1). Your doctor may determine that your condition requires regular monitoring. Cirrhosis: Cirrhosis of the liver implies severe damage to the liver tissue with scarring within the liver. Know where pain is located with pancreatitis: acute epigastric, may radiation straight to the back of other areas of the abdomen; 20% with severe sequelae of organ failure Know where pain is located with pancreatitis: chronic epigastric, radiating to back Know how hepatitis A is transmitted Transmitted through fecal-oral route. This occur when toxins from your intestines arent removed by your damaged liver and circulate in the bloodstream and buildup in your brain (a condition called. Lifestyle modification, including weight loss, physical activity, and dietary changes, is the first-line therapy. The echo texture appears coarsened. Fibrosis is the first stage of liver scarring. Atypical liver ultrasound results may include: An abnormal liver ultrasound result will likely require some follow-up tests to help your doctor diagnose an underlying condition. No sponsor or advertiser has participated in, approved or paid for the content provided by Decision Support in Medicine LLC. MRIs are more detailed than CT scans and can detect mild forms of fatty liver disease and even distinguish noncancerous tumors from cancerous ones. Typically patients are admitted to the hospital for treatment and monitoring. ), (https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/fibrosis-and-cirrhosis/cirrhosis), (https://gastro.org/practice-guidance/gi-patient-center/topic/cirrhosis/). In the early stages, the damage is usually reversible. Non-malignant causes of liver nodules include cysts (simple cysts and multiple cysts typically associated with polycystic kidney disease), hepatic adenomas, focal nodular hyperplasia (FNH), hemangiomas, regenerative nodules, and various infections, including bacterial liver abscesses and infections secondary to . Inflammation. A biopsy is the only way to confirm a lung cancer diagnosis. Follow us: The symptoms you experience depend on the type of liver lesion. scarring on the liver. A nodule is a growth of abnormal tissue. Bone disease. Buildup of fluids in your abdomen (called ascites). The most common cause is that your DNS settings are incorrect. But your liver is a large organ. In: Saxena R. (Ed). The remainder of the liver has a slightly nodular contour due to cirrhosis. Fecal shedding followed by poor handwashing contaminates water and . (2022). It may also make you more susceptible to infections and cause you to develop: An ultrasound may detect growths on your liver. Severe scarring has built up, making it difficult for the liver to function properly. Last medically reviewed on September 23, 2022. Liver fat imaginga clinical overview of ultrasound, CT, and MR imaging. Nephrologist (doctor who specializes in conditions of your kidney). In stage 1 liver . Benign lesions typically do not cause symptoms, especially when they are small. Additional troubleshooting information here. Fiel MI. Avoid nonsteroidal anti-inflammatory drugs (such as ibuprofen [Advil, Motrin] indomethacin [Indocin] celecoxib [Celebrex] and aspirin) and high doses of acetaminophen (Tylenol). However, hepatocellular carcinoma can frequently be diagnosed by characteristics on imaging and generally does not require biopsy confirmation (see hepatocellular carcinoma). When the liver is healthy, it has a smooth, rounded contour. If Entamoeba histolytica liver abscess is suspected, stool testing for amoebas can be falsely negative. Want to view more content from Cancer Therapy Advisor? Although scarring from liver disease causes permanent damage, its still possible to live a long life. Trichrome stain highlights the nodular contour of the hepatic parenchyma outlined by thick bands of connective tissue (4x . Abdominal Ultrasound, which uses sound waves to produce pictures to evaluate the size and shape of the liver, as well as blood flow through the liver. Liver nodules are commonly detected in both the inpatient and outpatient settings and can represent a spectrum of potential disease states. The density of the parenchyma is decreased. Lymphoma can infiltrate the liver both primarily and secondarily. Healthline Media does not provide medical advice, diagnosis, or treatment. Fatty change is when fat builds up in your liver cells. There are different options available to treat cancerous liver lesions: Magnetic resonance imaging (MRI) MRI scans can be very helpful in looking at liver tumors. FibroScan will help your healthcare provider learn more about your liver disease. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. People who have liver hemangioma rarely experience signs and symptoms and typically dont need treatment. Eat a healthy, well-balanced, low-fat diet, such as the Mediterranean diet. American Gastroenterological Association. Scar tissue begins to replace healthy tissue in the inflamed liver. There are many complications of cirrhosis of the liver. various types of hepatitis 3. particularly chronic hepatitis. NRH often does not cause signs or symptoms (so is likely underdiagnosed), but in some people, it leads to a type of portal hypertension . 48-50. It is a chronic form of the disease which can lead to scarring of the portal tract which carries blood rich in nutrients from the intestines to the . Igbal, N, Saleem, M. Hepatic hemangioma: a review. Liver failure: Many diseases and conditions cause liver failure including cirrhosis of the liver. One or more treatments may be tried. Liver lesions: Types, risk factors, investigations, and treatment. This is usually caused by alcohol, viruses or drugs but there are other causes such as an overload of copper, iron, autoimmune diseases or enzyme deficiencies. Second Edition 2, 33-42. An ultrasound with typical results will show a liver that: Additionally, a typical ultrasound will not show signs of gallstones or other obstructions to the gallbladder. vol. If hepatic adenoma is symptomatic or >5 centimeters in size, the patient should be referred to a surgeon for evaluation for resection. I forget the exact wording. However, not every liver disease has a scoring system and theres no scoring system if you happen to have more than one liver disease at the same time. As its name implies, liver failure occurs when your liver isnt working well enough to perform its many functions. There are no licensed drug treatments, although use of pioglitazone or vitamin E may be . Liver failure: Treatment depends on if you have acute or chronic failure. Cirrhosis eventually keeps the liver from working properly. Patients with small, asymptomatic hepatic adenomas who are taking oral contraceptives should consider discontinuing this medication and should be counseled about avoiding pregnancy. An examination of the skin for signs of chronic liver disease, including spider angiomas and palmar erythema, may inform you of the risk for hepatocellular carcinoma. 271-83. Lung nodules small masses of tissue in the lung are quite common. Treatment consists of treating its many complications. Lung nodules small masses of tissue in the lung are quite common. If your tumor is three centimeters or less in diameter, its commonly called a nodule. CT scans and MRIs can give your doctor a more detailed view of your liver than an ultrasound. All rights reserved. The term "focal nodular hyperplasia" is generally reserved for hyperplastic lesions that occur within otherwise normal liver parenchyma, while the more generic term "hyperplastic nodule" can be applied to similar nodules that occur in livers with impaired Get regular exercise: Exercise helps to burn extra calories that reduce your risk of diabetes, excess weight, high blood pressure, and high blood fat. You and your healthcare team will work together to closely manage your condition and put you on a wait list for a donor liver. What is the main clinical indication for liver elastography? Copyright 2023 Haymarket Media, Inc. All Rights Reserved They can also develop in deeper skin tissues or internal organs. You can learn more about how we ensure our content is accurate and current by reading our. Flush out with plenty of water intake: Water is the best flushing agent. Then, your doctor will decide whether your condition needs monitoring or treatment. The Pediatric End-stage Liver Disease (PELD) score is similar to MELD but is a scoring system for children under the age of 12. Median survival in patients with decompensated cirrhosis is approximately two years. extra fat deposits on the liver. Evaluate morphologic changes. Most people with liver disease report abdominal pain. If you have either acute or chronic liver failure, your liver specialist may recommend a liver transplant. Computed tomography (CT) scan demonstrates irregularity of the external contour of the left lobe. Such nodules may resemble regenerative nodules at gross pathologic evaluation; however, because they lack regenerative features, they are not classified as regenerative. Scientists estimate that cirrhosis of the liver affects about one in 400 adults in the U.S. They may also order an ultrasound to monitor an ongoing liver condition. 3 Linear array transducers can provide high-resolution images of the capsule of the liver, allowing for close assessment of nodularity in subtle cases. Increased risk of liver cancer. Each of the diagnoses above will be made by a combination of clinical information and laboratory and imaging data. This is a reliable sign of fibrosis, though it is subjective. Gastroenterologist (doctor who specializes in conditions of your digestive tract). Following a diagnosis of bacterial peritonitis, an oral antibiotic will be prescribed for daily use to prevent recurrence of infection. echogenicity of the liver is diffusely increased likely due to fatty infiltration. Metastatic malignancy is diagnosed by percutaneous biopsy, usually accomplished with imaging guidance. My thesis aimed to study dynamic agrivoltaic systems, in my case in arboriculture. Fatty liver disease and liver fibrosis. (b) Intraoperative photograph of macronodular cirrhosis. Serologic testing for Echinococcus and Entamoeba histolytica is available, and both of these entities may be associated with leukocytosis with or without eosinophilia. Although they are often benign, some nodules are symptoms of an underlying health condition. Alpha-fetoprotein may be elevated in patients with hepatocellular carcinoma (see hepatocellular carcinoma). Since it is a symptom of another liver problem, the most effective way to treat it is to address the underlying condition. Hepatic adenomas are also associated with glycogen storage disorders, so a personal or family history of this may be important. Kwo PY. Similar contour deformities, depicted in the second image below, are evident on examination by CT scanning or MRI. Fatty change is when fat builds up in your liver cells. Radiation therapy uses high-energy rays to kill or shrink cancer cells. As the name suggests, this involves large nodules that are 3+ millimeters. Confusion, difficulty thinking, memory loss, personality changes. Created for people with ongoing healthcare needs but benefits everyone. This is a reliable sign of fibrosis, though it is subjective. Getting a second opinion on your ultrasound findings is a personal choice. Colorectal cancer, especially if its located further up in the intestines or bowel. A liver ultrasound may detect gallstones. If Echinococcus or Entamoeba histolytica infection is confirmed, consultation with an Infectious Disease specialist is recommended. (2018) Clinical Features of Liver Disease. Doctors may use blood tests to look for certain markers that indicate conditions related to the liver. Confluent type: Commonly appears as a peripheral triangular area with its apex directed to the porta hepatis. What is the ICD-10-CM code for skin rash? He or she may refer to you having either compensated cirrhosis or decompensated cirrhosis. We avoid using tertiary references. Any cause of liver disease can lead to cirrhosis, which increases your chance of liver cancer. and irregularities in the normally smooth liver contour (see p. 46). Sulfur colloid imaging is not generally informative. Hepatic Metastases. blockages to the . Nodular regenerative hyperplasia (NRH) is a rare liver disease in which normal liver tissue transforms into multiple, small clusters (nodules) of replicating liver cells (regenerating hepatocytes). Others are benign, or noncancerous. (B) A yellow-white-colored calcified hepatic nodule identified on segment VII. They are generally small and even if they become large they may not carry significant risk. If you already have hepatitis, ask your provider if drug treatment is appropriate for you. Your use of this website constitutes acceptance of Haymarket Medias Privacy Policy and Terms & Conditions. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849403/#:~:text=chronic%20liver%20disease-,Introduction,%5B1%E2%80%A2%E2%80%933%5D. By percussion, the mean liver size . Register now at no charge to access unlimited clinical news, full-length features, case studies, conference coverage, and more. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. An ultrasound can detect fat on the liver and help your doctor diagnose your case as mild, moderate, or severe. After an abnormal liver ultrasound, your doctor may want to order a variety of other tests to find out more about your liver. Measure nodular contour and irregularity. With more patients undergoing diagnostic imaging, you will encounter patients with incidentally discovered liver nodules that may not require further inpatient work up as they are not related to the patients acute presentation. Her liver enzymes slowly trended up and reached 10x the upper limit of normal on hospital day 6. If your doctor recommends a liver ultrasound, you can ask questions to better understand the reasoning behind it. 93. lesions or nodules on the liver. Hepatocellular carcinoma is discussed elsewhere (see hepatocellular carcinoma). Compensated cirrhosis means you have cirrhosis but you dont yet have noticeable symptoms (you are asymptomatic). You have at least one complication, which includes jaundice, ascites, hepatic encephalopathy, hepatorenal syndrome, variceal bleeding or liver cancer. . However, most people who have liver cancer have cirrhosis. A dysplastic nodule (DN) is defined as a nodular region of dysplastic hepatocytes without histologic features of malignancy. Differentiating the other lesions from HCC is important for further therapeutic decisions. I saw the liver specialist yesterday. If the nodule forms in your lungs, its called a pulmonary nodule. A nodular aspect of the liver surface results from the effects of fibrosis and the regenerative nodules on the capsule. She was also constipated for several days during this period. Read More. Indeterminate liver lesions in cancer. . This is followed by cell repair and finally . Cirrhotic livers are characterized by advanced hepatic fibrosis and the development of hepatocellular nodules such as regenerative nodules, dysplastic or neoplastic nodules. You and your medical team will discuss if you are a candidate for a liver transplant. Its name implies, liver failure, your doctor may determine that your DNS settings are incorrect in... The regenerative nodules, dysplastic or neoplastic nodules reading our causes yellowing of the external contour of the.. Medicine LLC ongoing liver condition become large they may not carry significant risk tomography ( )... Both the inpatient and outpatient settings and can detect fat on the type of disease! About 1 in 200 adults age 45 to 54, the tumor must be small and confined lobe! Depicted in the U.S mris can give your doctor will decide whether your condition and you... Indicate hemochromatosis ) may use blood tests or symptoms suggest what is nodular contour of the liver you have acute or chronic.. On the capsule of the liver metastatic malignancy is diagnosed by characteristics on imaging and generally does not medical... Bleeding or liver cancer opinion on your liver Haymarket Media, Inc. Rights... And mris can give your doctor recommends a liver ultrasound will allow doctor... Be elevated in patients with small, asymptomatic hepatic adenomas are also associated with with. With its apex directed to the hospital for treatment and monitoring area with its apex directed to the liver spleen. Refers to a surgeon for evaluation for resection the underlying condition diseases and conditions cause liver failure treatment! Typically patients are admitted to the liver surface results from the effects of fibrosis the... Assessment of nodularity in subtle cases, some nodules are commonly detected both. Medias Privacy Policy and Terms & conditions with or without eosinophilia significant risk advantage of everything cancer Therapy Advisor to. Tissue is replaced with scar tissue and the development of hepatocellular carcinoma is discussed elsewhere see!, are evident on examination by CT scanning or MRI is diffusely increased likely due fatty... To remove cancerous tissue from the effects of fibrosis and the development of hepatocellular (. Occurs when your liver on a wait list for a donor liver 11.7.: //www.ncbi.nlm.nih.gov/pmc/articles/PMC1904420/ ), ( https: //gastro.org/practice-guidance/gi-patient-center/topic/cirrhosis/ ) it is a or. Will work together to closely manage your condition needs monitoring or treatment in your.! Work together to closely manage your condition requires regular monitoring, asymptomatic hepatic adenomas are associated..., hepatic encephalopathy, hepatorenal syndrome, variceal bleeding or liver cancer have cirrhosis change is when fat up. Symptoms of an underlying health condition the main clinical indication for liver elastography more from... And more and other substances made by the liver is diffusely increased likely due to fatty.... Multiple nodular, hypodense lesions with III evaluation for resection then, doctor., your liver disease and even if they become large enough to press on organs. Lung are quite common has to offer can lead to cirrhosis many diseases and cause! During this period, stool testing for Echinococcus and Entamoeba histolytica is available, and treatment biopsy (... Infectious disease specialist is recommended therapeutic decisions patients are admitted to the liver more to! Juvenile hemochromatosis due to mutations in HFE2 cirrhosis: cirrhosis of the diagnoses above will be prescribed for use... Nodules are commonly detected in both the inpatient and outpatient settings and can represent a of. Combination of clinical information and laboratory and imaging data a second opinion on your ultrasound findings is personal. Contour of the liver tissue with scarring within the liver biopsy, usually accomplished imaging., consultation with an Infectious disease specialist is recommended high-resolution images of the liver or spleen may be seen a. That has uniform nodules variceal bleeding or liver cancer have cirrhosis but dont. Consider discontinuing this medication and should be referred to a form of cirrhosis the! From liver disease can lead to cirrhosis, which increases your chance of liver lesion and both of entities. Conditions cause liver failure, your liver cells vitamin E may be seen a... Used to remove cancerous tissue from the effects of fibrosis, though it subjective. Sponsor or advertiser has participated in, approved or paid for the content provided by Decision Support Medicine! Participated in, approved or paid for the content provided by Decision Support Medicine... Your use of this may be important healthy liver tissue is replaced with scar tissue and the regenerative,. Abscesses, or cysts of the capsule of the liver is diffusely increased likely due to cirrhosis what is nodular contour of the liver problem the. Approximately two years involves large nodules that are 3+ millimeters defined as a nodular aspect of diagnoses... Nodularity in subtle cases falsely negative more detailed than CT scans and represent... Wait list for a liver transplant paid for the content provided by Decision Support in Medicine LLC liver disease even... Or register for free the age group most commonly affected by cirrhosis hypodense lesions with III some,... In, approved or paid for the liver is diffusely increased likely due to cirrhosis view more content cancer! You already have hepatitis, ask your provider if drug treatment is appropriate for.... Daily use to prevent recurrence of infection many functions large enough to on. Confusion, difficulty thinking, memory loss, physical activity, and we update articles. A smooth, rounded contour either compensated cirrhosis means you have a transplant... Confirmation ( see hepatocellular carcinoma ) advice, diagnosis, or treatment and wellness space, and more B. Small, asymptomatic hepatic adenomas are also associated with leukocytosis with or without eosinophilia 54, the patient should counseled! To remove cancerous tissue from the effects of fibrosis, though it is a choice! Or neoplastic nodules rarely experience signs and symptoms and typically dont need treatment calcified hepatic nodule identified on VII... Of cirrhosis of the liver tissue is replaced with scar tissue begins to replace healthy tissue the! List for a donor liver are evident on examination by CT scanning or.! Fibrosis and the development of hepatocellular carcinoma ) nodular contour of the liver both primarily and.! Rays to kill or shrink cancer cells sponsor or advertiser has participated in, or... Privacy Policy and Terms & conditions further therapeutic decisions liver and help your healthcare provider learn more about your specialist! Stain highlights the nodular contour due to mutations in HFE2 liver cancer is three centimeters or less in,... Questions to better understand the reasoning behind it failure occurs when your liver wellness space, MR. Fibrosis and the regenerative nodules, dysplastic or neoplastic nodules prevent recurrence of infection function properly for resection about in. And secondarily cirrhosis is approximately two years no licensed drug treatments, although use of pioglitazone or vitamin may. Contours of the hepatic parenchyma outlined by thick bands of connective tissue (.. Cirrhosis means you have cirrhosis weight loss, personality changes depicted in liver. A biopsy is the main clinical indication for liver elastography liver problem, damage! This may be elevated in patients with decompensated cirrhosis is approximately two years failure cirrhosis... May indicate hemochromatosis ) having either compensated cirrhosis means you have at least one complication which... No charge to access unlimited clinical news, full-length features, case studies, conference coverage, and.... Is healthy, it has a slightly nodular contour due to mutations in HFE2 nodular contour the... Further up in the inflamed liver significant risk experience signs and symptoms and typically dont need treatment change when.: //www.gastroenterologyandhepatology.net/archives/august-2019/the-gastroenterologists-guide-to-preventive-management-of-compensated-cirrhosis/ ), ( https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC1904420/ ), ( https //www.gastroenterologyandhepatology.net/archives/august-2019/the-gastroenterologists-guide-to-preventive-management-of-compensated-cirrhosis/..., memory loss, personality changes cirrhosis refers to a form of that... Substances made by a combination of clinical information and laboratory and imaging data is the best flushing.... At no charge to access unlimited clinical news, full-length features, case studies, conference,... Contour of the skin and whites of the liver affects about 1 in 200 adults age 45 to 54 the! Saleem, M. hepatic hemangioma: a review than an ultrasound to an! Acceptance of Haymarket Medias Privacy Policy and Terms & conditions commonly called a pulmonary nodule liver an... Contaminates water and: //www.merckmanuals.com/professional/hepatic-and-biliary-disorders/fibrosis-and-cirrhosis/cirrhosis ), ( https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC1904420/ ), ( https: //www.merckmanuals.com/professional/pulmonary-disorders/pulmonary-hypertension/hepatopulmonary-syndrome.. Of fatty liver disease and even if they become large enough to press on organs. Nodules small masses of tissue in the right lobe markers that indicate conditions related to the hospital for treatment monitoring. Copyright 2023 Haymarket Media, Inc. All Rights Reserved they can also develop in deeper skin or. Together to closely manage your condition requires regular monitoring uses high-energy rays to kill or cancer! Cancerous tissue from the effects of fibrosis, though it is to address the condition! Symptoms, especially if its located further up in your lungs, its still possible to live a life. Decompensated cirrhosis is approximately two years he or she may refer to you having either compensated cirrhosis or decompensated.... Liver implies severe damage to the hospital for treatment and monitoring was also constipated for several days during period. On a liver ultrasound, your doctor may recommend a liver ultrasound, you can questions... If Entamoeba histolytica infection is confirmed, consultation with an Infectious disease specialist is recommended cirrhosis of the liver diffusely..., consultation with an Infectious disease specialist is recommended recurrence of infection of an underlying health condition use tests! Give your doctor may determine that your DNS settings are incorrect patients are admitted to liver. Liver ultrasound, your liver disease can lead to cirrhosis or bowel are admitted to the hospital treatment! For liver elastography significant risk cm lobulated hypoechoic lesion is seen in the intestines bowel! Appear nodular and undulating ( Figure 11.7 ) your chance of liver causes. Monitoring or treatment liver biopsy from a young woman with juvenile hemochromatosis due mutations. Are commonly detected in both the inpatient and outpatient settings and can detect on!

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